SciShow: The Return of Thalidomide

Teacher or professor: SciShow
Subject: Science
Content of the Lesson: Thalidomide is the infamous drug at the heart of one of the world's worst drug safety catastrophes in modern medicine. And yet, more recent research is finding that thalidomide is still worth using, despite the risks. So what makes this drug that causes life-altering fetal abnormalities such a good thing? Hosted by: Hank Green (he/him) ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Alisa Sherbow, Dr. Melvin Sanicas, Harrison Mills, Adam Brainard, Chris Peters, charles george, Piya Shedden, Alex Hackman, Christopher R, Boucher, Jeffrey Mckishen, Ash, Silas Emrys, Eric Jensen, Kevin Bealer, Jason A Saslow, Tom Mosner, Tomás Lagos González, Jacob, Christoph Schwanke, Sam Lutfi, Bryan Cloer ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/ TikTok: https://www.tiktok.com/@scishow Twitter: http://www.twitter.com/scishow Instagram: http://instagram.com/thescishowFacebook: http://www.facebook.com/scishow #SciShow #science #education #learning #complexly ---------- Sources: https://pubmed.ncbi.nlm.nih.gov/35771402/ https://journals.sagepub.com/doi/abs/10.1177/1078155220975825?journalCode=oppa https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540221/ https://www.dana-farber.org/newsroom/news-releases/2018/after-60-years--scientists-uncover-how-thalidomide-produced-birth-defects/ https://ar.iiarjournals.org/content/35/11/5767 https://www.accessdata.fda.gov/scripts/cder/rems/index.cfm?event=IndvRemsDetails.page&REMS=58 https://pubmed.ncbi.nlm.nih.gov/22348778/ https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/cereblon https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737249/ https://pubmed.ncbi.nlm.nih.gov/32125404/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265446/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931443/ https://pubmed.ncbi.nlm.nih.gov/22650377/ https://thalomidrems.com https://fda.report/media/86286/Thalomid--Patient-Guide.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362654/ https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt196563303 https://www.washingtonpost.com/archive/lifestyle/wellness/2000/01/04/thalidomides-legacy/c7bc3a6e-4c22-49b1-929d-0d117f085d0e/ https://www.washingtonpost.com/wp-srv/washtech/longterm/thalidomide/keystories/patient062089.htm https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631033/ Images: https://commons.wikimedia.org/wiki/File:Pack_of_Thalidomide_tablets.jpg https://www.gettyimages.com/detail/photo/closeup-pharmacist-hand-holding-medicine-box-royalty-free-image/897885148?phrase=pharmaceutical&adppopup=true https://www.gettyimages.com/detail/photo/photo-of-the-fetus-on-an-ultrasound-scan-and-few-royalty-free-image/1297678794?adppopup=true https://commons.wikimedia.org/wiki/File:NCP14053.jpg https://www.gettyimages.com/detail/video/slow-motion-of-pipette-dripping-stock-footage/1405058944?adppopup=true https://www.gettyimages.com/detail/photo/thalidomide-molecule-on-white-royalty-free-image/508726549?phrase=thalidomide&adppopup=true https://www.gettyimages.com/detail/photo/spreading-royalty-free-image/172153877?phrase=hiv&adppopup=true https://www.gettyimages.com/detail/photo/crohns-disease-royalty-free-image/912219418?phrase=Crohn%27s+disease&adppopup=true https://commons.wikimedia.org/wiki/File:TNFa_Crystal_Structure.rsh.png https://www.gettyimages.com/detail/photo/cell-attacking-a-cancer-cell-royalty-free-image/1383260152?phrase=cancer+cells+immune+system&adppopup=true https://www.gettyimages.com/detail/illustration/step-of-angiogenesis-medical-learning-about-royalty-free-illustration/1370326138?phrase=angiogenesis&adppopup=true https://www.gettyimages.com/detail/video/blood-cells-pulsing-down-artery-hd-stock-footage/883866318?adppopup=true https://www.gettyimages.com/detail/video/hela-cells-in-culture-stock-footage/519856224?adppopup=true https://www.gettyimages.com/detail/photo/cancer-malignant-cells-royalty-free-image/1372020529?phrase=cancer+treatment&adppopup=true https://www.gettyimages.com/detail/illustration/multiple-myeloma-is-a-cancer-of-the-bone-royalty-free-illustration/881911948?phrase=myeloma&adppopup=true https://www.gettyimages.com/detail/photo/senior-man-cant-remember-which-pill-to-take-royalty-free-image/1264979561?phrase=medication+mix+up&adppopup=true https://www.gettyimages.com/detail/video/solving-the-test-exam-paper-choices-stock-footage/472947795?adppopup=true https://www.gettyimages.com/detail/video/newborn-baby-and-little-hand-stock-footage/864018480?adppopup=true https://www.gettyimages.com/detail/video/white-capsules-fall-from-a-metal-conveyor-automatic-line-stock-footage/1419962583?adppopup=true


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