SciShow: These AIs Are About to Revolutionize Biology

Teacher or professor: SciShow
Subject: Science
Content of the Lesson: Even though proteins are fundamental to life, it’s hard to predict what they look like. But two independent groups announced that they’d cracked it, and it’s all thanks to some seriously clever artificial intelligence. Hosted by: Hank Green SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Chris Peters, Matt Curls, Kevin Bealer, Jeffrey Mckishen, Jacob, Christopher R Boucher, Nazara, charles george, Christoph Schwanke, Ash, Silas Emrys, Eric Jensen, Adam, Brainard, Piya Shedden, Alex Hackman, James Knight, GrowingViolet, Sam Lutfi, Alisa Sherbow, Jason A Saslow, Dr. Melvin Sanicas, Melida Williams ---------- Looking for SciShow elsewhere on the internet? SciShow Tangents Podcast: http://www.scishowtangents.org Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Instagram: http://instagram.com/thescishow ---------- Sources: https://www.nature.com/articles/s41586-021-03819-2 https://www.nature.com/articles/d41586-021-01968-y https://science.sciencemag.org/content/early/2021/07/14/science.abj8754 https://www.sciencemag.org/news/2021/07/researchers-unveil-phenomenal-new-ai-predicting-protein-structures https://www.ipd.uw.edu/2021/07/rosettafold-accurate-protein-structure-prediction-accessible-to-all/ https://www.thetimes.co.uk/article/demis-hassabis-interview-the-kid-from-the-comp-who-founded-deepmind-and-cracked-a-mighty-riddle-of-science-g3v3z9b80 https://www.technologyreview.com/2020/11/12/1011944/artificial-intelligence-replication-crisis-science-big-tech-google-deepmind-facebook-openai/ https://www.technologyreview.com/2020/11/30/1012712/deepmind-protein-folding-ai-solved-biology-science-drugs-disease/ https://news.cancerresearchuk.org/2020/12/23/what-could-deepmind-solving-the-protein-folding-problem-mean-for-cancer-research/ https://www.theguardian.com/technology/2020/nov/30/deepmind-ai-cracks-50-year-old-problem-of-biology-research https://arstechnica.com/science/2021/07/google-details-its-protein-folding-software-academics-offer-an-alternative/ https://www.vox.com/future-perfect/22045713/ai-artificial-intelligence-deepmind-protein-folding https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology https://www.pnas.org/content/117/3/1496 https://emerj.com/ai-sector-overviews/deepmind-alphafold/ https://www.chemistryworld.com/opinion/behind-the-screens-of-alphafold/4012867.article https://www.dw.com/en/what-are-proteins-and-why-do-they-fold/a-55815679 https://www.nature.com/articles/d41586-020-03348-4 https://www.nature.com/articles/s41586-021-03828-1 https://www.nature.com/articles/d41586-021-02025-4 https://www.theguardian.com/technology/2021/jul/22/ai-firm-deepmind-puts-database-building-blocks-life-human-protein-structure-free-online https://www.nature.com/articles/d41586-021-02037-0 http://www.imgt.org/IMGTeducation/Aide-memoire/_UK/aminoacids/abbreviation.html https://www.ncbi.nlm.nih.gov/books/NBK26830/ https://predictioncenter.org/casp14/doc/CASP14_press_release.html https://www.youtube.com/watch?v=gg7WjuFs8F4 https://deepmind.com/blog/article/AlphaStar-Grandmaster-level-in-StarCraft-II-using-multi-agent-reinforcement-learning https://deepmind.com/blog/article/alphazero-shedding-new-light-grand-games-chess-shogi-and-go https://www.nobelprize.org/prizes/chemistry/1972/summary/ https://www.frontiersin.org/articles/10.3389/fmolb.2020.00009/full https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402234/ https://www.youtube.com/watch?v=gLsC4wlrR2A https://www.nature.com/articles/d41586-021-02265-4 Images: https://commons.wikimedia.org/wiki/File:Hexokinase_ball_and_stick_model,_with_substrates_to_scale_copy.png https://commons.wikimedia.org/w/index.php?curid=35438148 https://wellcomecollection.org/works/u35a5ang https://commons.wikimedia.org/wiki/File:Parasagittal_MRI_of_human_head_in_patient_with_benign_familial_macrocephaly_prior_to_brain_injury_(ANIMATED).gif https://commons.wikimedia.org/wiki/File:Target3dsmRib_354predictedModels_CASP8.jpg https://commons.wikimedia.org/wiki/File:1GZX_Haemoglobin.png https://www.eurekalert.org/multimedia/662832 https://commons.wikimedia.org/wiki/File:Foldit_screenshot_2.jpg https://commons.wikimedia.org/wiki/File:Neural_network_example.svg https://commons.wikimedia.org/wiki/File:ACBP_MSM_from_Folding@home.tiff https://commons.wikimedia.org/wiki/File:Structural_coverage_of_the_human_cyclophilin_family.png https://commons.wikimedia.org/wiki/File:Protein_Imager_molecular_rendering_example_3_CsgFG_complex.png https://commons.wikimedia.org/wiki/File:153-PyruvateDehydrogenaseComplex_pyruvatedehydrogenase.tif https://commons.wikimedia.org/wiki/File:Chaperonin_1AON.png https://commons.wikimedia.org/wiki/File:Protein_structure_examples.png


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