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SciShow: 6 Reasons We Have to Say a Study Was "In Mice"
Teacher or professor: SciShow
Subject: Science
Content of the Lesson: A lot of our videos include the disclaimer "Mice aren't people". But why do we keep saying this, and if rodent studies aren't effective, why do we keep using them? Hosted by: Stefan Chin SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org ---------- Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow ---------- Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever: Matt Curls, Sam Buck, Christopher R Boucher, Avi Yashchin, Adam Brainard, Greg, Alex Hackman, Sam Lutfi, D.A. Noe, Piya Shedden, Scott Satovsky Jr, Charles Southerland, Patrick D. Ashmore, charles george, Kevin Bealer, Chris Peters ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow ---------- Sources: Intro: https://www.genome.gov/10005834/background-on-mouse-as-a-model-organism Alzheimer's disease: https://www.nia.nih.gov/health/what-happens-brain-alzheimers-disease https://www.nature.com/articles/d41586-018-05722-9 https://www.biospace.com/article/a-look-at-biogen-s-big-bet-on-the-holy-grail-of-science-and-mdash-alzheimer-s-/ http://investors.biogen.com/news-releases/news-release-details/biogen-and-eisai-discontinue-phase-3-engage-and-emerge-trials https://www.nature.com/articles/s41586-019-1506-7 Multiple sclerosis: https://medlineplus.gov/multiplesclerosis.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154595/ https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(87)92863-7/fulltext https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586507/ https://www.degruyter.com/view/j/revneuro.2019.30.issue-1/revneuro-2018-0002/revneuro-2018-0002.xml Hepatitis B: https://www.cdc.gov/hepatitis/hbv/index.htm https://www.nap.edu/catalog/4887/review-of-the-fialuridine-fiau-clinical-trials http://discovermagazine.com/1994/mar/thecurethatkille345 https://www.ncbi.nlm.nih.gov/pubmed/16595656 http://perspectivesinmedicine.cshlp.org/content/5/12/a021451.full Tuberculosis: https://www.cdc.gov/tb/publications/faqs/qa_introduction.htm https://medlineplus.gov/tuberculosis.html https://www.ncbi.nlm.nih.gov/pubmed/11288517 https://www.ncbi.nlm.nih.gov/pubmed/20819249 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798013/ https://www.jimmunol.org/content/172/5/2731#sec-6 Saccharin: https://www.nytimes.com/1977/06/19/archives/fda-says-new-canadian-study-reinforces-its-ban-of-saccharin.html https://academic.oup.com/annonc/article/15/10/1460/170200 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009921/ https://www.ncbi.nlm.nih.gov/pubmed/9428778 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591507/ https://www.niehs.nih.gov/news/newsroom/releases/2000/may15/index.cfm https://www.foodserviceandhospitality.com/health-canada-approves-saccharin-sweeteners-canada/ Microbiome: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991899/ https://www.nature.com/articles/s41598-018-24342-x#Sec8 https://www.health.harvard.edu/blog/stool-transplants-are-now-standard-of-care-for-recurrent-c-difficile-infections-2019050916576 https://dmm.biologists.org/content/8/1/1#sec-16 https://www.the-scientist.com/news-opinion/mouse-genetics-shape-the-gut-microbiome-more-than-their-environment-66238 https://www.eurekalert.org/pub_releases/2019-08/niod-mc072919.php Closing: https://www.nabr.org/animal-research-into-the-worlds-five-deadliest-diseases/ https://commons.wikimedia.org/wiki/File:Neuron.svg https://commons.wikimedia.org/wiki/File:1FG9_IFNG_IFNG.png#/media/File:1FG9_IFNG_IFNG.png
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