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Do We Need These Omicron-Specific Boosters? (w/Dr. Paul Offit)
The vaccine expert is less than impressed with evidence to support the Omicron BA.4/5 "bivalent" booster shots now rolling out for everyone 12 and older. A must-watch deep dive into some science! We also talk polio and monkeypox and flu 👍 Topics & Timestamps: 00:00 Intro 1:10 A brief history of the Covid vaccines, groups that benefit from boosting 5:12 Incubation periods and vaccination "goals," preventing infection vs. severe disease 10:54 Bivalent vaccine, the FDA's EUA approach, crucial dosing issues (ancestral strain vs. bivalent) 17:15 BA.4/5 booster immunogenicity data (or lack thereof), mouse data & vax safety profile 21:40 Why Paul himself would pass on the new booster, incubation periods, why Covid zero is a fantasy 24:28 Paul's "perfect" bivalent vaccine 25:37 Yearly targeted boosters, myocarditis and the Thai children's study 28:39 BA.4/5: MIS-C, boosters & long Covid, data from JAMA's Italian study 31:28 Comparing BA.4/5 & the yearly flu vax, timing of the yearly flu shot 38:45 Polio's resurgence, injected inactivated vs. live oral polio vaccines, the role of sanitation 48:05 Monkeypox and a history of smallpox vaccines 56:43 Reflection w/Dr. Offit: what he's gotten right, what he's gotten wrong and where to go from here 1:01:57 Final thoughts Transcript and links to more shows: https://zdoggmd.com/paul-offit-10 Video archive, audio podcast, music parodies, Supporter Tribe membership, merch, social media, and email: https://lnk.bio/zdoggmd Support us with a 1-time donation and get a personal email thank you from me: https://paypal.me/zdoggmd More about Dr. Z: https://zdoggmd.com/about-z
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